A Predicta Bioactive Bulk syringe which is a bioactive fill composite with brown tips
Predicta Bioactive Bulk paste a bioactive bulk-fill composite on one side and on another side we see the composite is being applied on a molar tooth model
Predicta Bioactive Bulk syringe A2/B2 regular viscosity, a bioactive bulk-fill composite with brown dispensing tip.
Predicta Bioactive Bulk syringe A2/B2 low viscosity, a bioactive bulk-fill composite with brown dispensing tip.
Predicta Bioactive Bulk syringe A1/B1 regular viscosity, a bioactive bulk-fill composite with brown dispensing tips
Predicta Bioactive Bulk syringe A1/B1 low viscosity, a bioactive bulk-fill composite with brown dispensing tips

Predicta® Bioactive Bulk

€129.37

SKU: S610 Category: Brand:

Dual-cure, bioactive universal composite for chairside bulk-fill restorative procedures. Unlimited cure depth, single-increment placement protocol.

Terms of delivery

Description

Predicta® Bioactive Bulk is a universal, dual-cure bioactive bulk-fill composite that streamlines restorative procedures while maintaining performance and longevity. It is designed to fill any size cavity preparation all the way up to the occlusal surface—without the need for layering—making it particularly effective for posterior restorations and as an amalgam substitute.

Moreover, this bioactive bulk-fill composite promotes long-term tooth health through the continuous release of calcium and phosphate ions. Additionally, it releases and recharges fluoride ions, contributing to remineralization and the formation of mineral apatite at the tooth-material interface. As a result, these bioactive properties help support tooth structure and reduce the risk of secondary caries.

Key Features of using Predicta Bioactive Bulk

  • Dual-cure for unlimited depth of cure – Ensures complete polymerization in deep preparations or under indirect restorations.

  • Fluorescent for natural appearance – Enhances esthetics and visibility under curing and diagnostic lights.

  • Multiple viscosities and shades – Available in flowable and packable consistencies to suit different clinical cases.

  • Highly radiopaque – Improves diagnostic confidence on X-rays.

  • Nanohybrid versatility – Offers excellent polishability and esthetic blending.

  • Strong and durable – Withstands occlusal forces in high-stress posterior zones.

  • Indicated for Class I–V restorations – Suitable for a broad range of clinical applications, from shallow to deep cavities.

  • Highly polishable – Maintains long-lasting surface luster and smoothness.

Predicta® Bioactive Bulk is compatible with all standard adhesive systems and is delivered in an easy-to-use syringe format for precise placement. Its ability to support minimally invasive dentistry while delivering long-term functional and esthetic outcomes makes it a valuable tool in any restorative workflow.

Download the brochure to learn more.

Predicta® Bioactive Bulk – Physical Properties Chart
Physical Property Regular
Viscosity		 Low
Viscosity
Light-cure setting time 40 sec 40 sec
Depth of light cure 4 mm 4 mm
Initial self-cure setting time at 37°C ≥5 min ≥5 min
Percentage filler by weight 67.6% 67.0%
Flexural strength, average 135 MPa 131.7 MPa
Compressive strength, average 355 MPa 355 MPa
Diametral tensile strength, average 52 MPa 52.0 MPa
Polymerization shrinkage, linear, light cured for 20 seconds 2.60% 3.40%
DC shrinkage at 37°C, with a two-minute self-cure followed by a 20-second light cure 1.52% 1.52%
Radiopacity 280 280
Surface hardness
(Barcol hardness)		 ≥70 ≥70
Wear resistance
(wear rate)		 0.50% 0.77%
Fluorescence Yes Yes
BPA Yes Yes
Manufacturer test results, Parkell Inc.

Additional references

https://www.nature.com/articles/s41598-025-86595-7

https://bmcoralhealth.biomedcentral.com/articles/10.1186/s12903-023-03814-1

https://www.nature.com/articles/s41405-024-00209-4

https://www.sciencedirect.com/science/article/pii/S0020653922002672

https://www.researchgate.net/publication/364401403_The_Cytotoxicity_and_Genotoxicity_of_Bioactive_Dental_Materials

For use by licensed dental professionals only.

Videos

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Predicta® Bioactive Bulk | Product insight by Dr. Manouchehr Kiaei
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Predicta® Bioactive Bulk | Product insight by Dr. Sjobbe Besseling
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Four Quick Tips for Using Predicta® Bioactive Bulk

Information

Description
File name
Language
Instruction for Use
English, Danish, German, Spanish, Finnish, French, Italian, Dutch, Norwegian, Swedish, Greek, Portuguese, Bulgarian, Hungarian, and Romanian
Safety Data Sheet
English, Danish, German, Greek, Spanish, Finnish, French, Italian, Norwegian, Polish, Dutch and Swedish
Safety Data Sheet
English, Danish, German, Greek, Spanish, Finnish, French, Italian, Norwegian, Polish, Dutch and Swedish
In vitro remineralization of adjacent interproximal enamel carious lesions in primary molars using a bioactive bulk-fill composite
English
Dentine Remineralisation Induced by “Bioactive” Materials through Mineral Deposition: An In Vitro Study
English
Mechanical properties of modern restorative "bioactive" dental materials - an in vitro study
English
The Cytotoxicity and Genotoxicity of Bioactive Dental Materials
English
The demineralization resistance and mechanical assessments of different bioactive restorative materials for primary and permanent teeth: an in vitro study
English
Predictable Management of a Deep Carious Lesion with Bioactive Restorative Materials
English
Bioactivity of Dental Restorative Materials: FDI Policy Statement
English
An in vitro micro‐CT assessment of bioactive restorative materials interfacial adaptation to dentin
English
Parkell® Bioactive Bulk Restorative - Release study by Uppsala University (Sweden)
English
Product Catalogue - Parkell Europe 2026 (EN)
English

“One of the best characteristics of Predicta is its dual-cure capability. This enables the dentist to fill the cavity in one increment, no matter how large the restoration may be. That saves time and minimizes the shrinkage tension in the tooth restoration interface. Being able to bulk fill in a single increment also minimizes the risk of contamination, as the whole procedure can be done much more quickly and efficiently.” – Manouchehr Kiaei, DDS, Sweden

“Predicta Bioactive Bulk is a unique restorative material; it is dual-curing, bioactive and well-suited for bulk application. There is no need for occlusal layering or to add a different composite on top of the bulk restoration. I love the ease with which large restorations can be made; it is a time-saver! The initial chemical curing process is nice and short, but not too short! My patients do not experience any pain after the application of the restoration. The restorations polish well and still look like new after several years.” –   Sjobbe Besseling, DDS, Netherlands

“Having something that is bioactive—something that lays down well and will create new hydroxyapatite or new tooth structure—is very beneficial.” –  Sheldon Seidman, DDS, USA

“I like Predicta Bulk because it fills in well and sets well. I am happy with how I’m able to trim and polish it, and the color is good. I have found that it flows to the walls of the preparation better than some of the other bulk-fills I have previously used.” – Sheldon Seidman, DDS, USA

“Predicta Bioactive Bulk has amazing esthetics while providing the security of dual-cure chemistry and bioactivity.” – Gregg Helvey, DDS, MAGD, CDT, USA

“It’s really the trifecta — you have a bulk-fill that’s dual-cure with bioactivity, which means you’ve got everything you need.” – Sheldon Seidman, DDS, USA

“At My Dental Company, we only use the highest quality of products. We are consistently looking for what products out there are the best. Parkell and their Predicta Bioactive line is one of those products and we love it. The more that we can create those ongoing and exceptional outcomes for our patients, that is really where we want to be in dentistry.” – Douglas Olson, DDS, USA

“I’ve been using Predicta Bulk to restore Class I and Class II cavities in molars and premolars for two years now. Predicta Bulk has consistently proven to have excellent properties and results. I placed over 2,000 restorations, many of which have been very large, and the failure rate of those restorations has been less than 0.5%.” – Manouchehr Kiaei, DDS, Sweden

“When I started using Predicta, I was pleasantly surprised by the excellent color adaptability of this composite. Using only the A2/B2 shade, I have been able to match almost every tooth shade.” – Manouchehr Kiaei, DDS, Sweden

Predicta Bioactive Bulk A1/B1 Regular Viscosity
SKU S615
Industry Dental
Category Universal Composite
Net Weight 9.25 g
Curing Type Dual curing
Predicta Bioactive Bulk A1/B1 Low Viscosity
SKU S610
Industry Dental
Category Universal Composite
Net Weight 9.25 g
Curing Type Dual curing
Predicta Bioactive Bulk A2/B2 Regular Viscosity
SKU S616
Industry Dental
Category Universal Composite
Net Weight 9.25 g
Curing Type Dual curing
Predicta Bioactive Bulk A2/B2 Low Viscosity
SKU S611
Industry Dental
Category Universal Composite
Net Weight 9.25 g
Curing Type Dual curing

FAQ

Bioactivity! Bioactive materials release calcium, phosphate and fluoride, which trigger the formation of a protective layer of mineral apatite, the predominant element found in both enamel and dentin. They are also dual cure, eliminating the worry in incomplete cure of materials leading to sensitivity and failure of restoration.

Predicta Bulk is a highly polishable universal composite, that can be used in all areas of the mouth, and is indicated for Class I through V restorations. Predicta Core is indicated for core build-ups and as a post cement. The addition of Zirconia helps provide a strong and stable support for crowns made of zirconia, lithium disilicate, porcelain, PFM and metal.

Materials must always be brought to room temperature prior to use.

The most likely reason a dual-cure composite doesn’t set is failure to double bleed.

Remove the shipping cap. Extrude a small amount of material onto pad until it flows freely from both orifices. Place mixing tip on cartridge and extrude a pea sized amount onto pad prior to placing in mouth.

Regular viscosity is used ideally for large restorations where stability is desirable and material drift is not. Low viscosity is recommended for smaller preps where the ability to flow and adapt into tighter spaces is preferred and for better adaptation of hard to access prep margins and line angles. Both HV and LV versions can be used in all restorative situations. These guidelines are an aid when choosing a bulk-fill that more closely matches your needs.

No, Predicta Bioactive Bulk is a nanohybrid, it is optimized for wear resistance and is highly polishable.

Like all dual-cure composites there will be some self-etching bonding agents that are not compatible with Predicta Bulk, however all good quality universal bonding agents are compatible with Predicta Bioactive Bulk.

Clinical Literature

Explore published in vitro research evaluating Predicta® Bioactive Bulk, including studies of enamel and dentin remineralization, demineralization resistance, and mechanical properties.

In vitro remineralization of adjacent interproximal enamel carious lesions in primary molars
Phyo et al. · 2024 · BMC Oral Health

Phyo et al. (2025), in a study published in BMC Oral Health, assessed Predicta® Bioactive Bulk, a bioactive bulk-fill composite, and Filtek™ Z350 in artificial interproximal enamel carious lesions in extracted primary molars.

Key findings
  • Under the conditions tested, Predicta produced significantly greater surface microhardness recovery than Filtek™ Z350.
  • SEM images showed greater mineral deposition in the Predicta and high-viscosity glass ionomer groups than in the conventional resin-based composite group.
  • Predicta’s surface microhardness recovery and fluoride content were similar to those of the high-viscosity glass ionomer cement.
“

The highest percentage of surface microhardness recovery (%SMHR) was found in the Predicta® Bioactive Bulk group, which was significantly different from the Filtek™ Z350 group.

“

SEM images illustrated greater mineral deposition in the HVGIC and Predicta bioactive bulk-fill composite groups compared with conventional resin-based composite.

Study context

This was an in vitro study using extracted primary molars and artificially created enamel lesions. It does not establish clinical outcomes in patients.

Reference

Phyo, W. M., Saket, D., da Fonseca, M. A., Auychai, P., & Sriarj, W. (2024). In vitro remineralization of adjacent interproximal enamel carious lesions in primary molars using a bioactive bulk-fill composite. BMC Oral Health, 24, Article 37.


View Published Study

The demineralization resistance and mechanical assessments of different bioactive restorative materials for primary and permanent teeth
Ibrahim et al. · 2024 · BDJ Open

Ibrahim et al. compared Predicta® Bioactive Bulk-Fill with Beautifil Kids SA and a conventional non-bioactive flowable composite.

Key findings
  • Following pH cycling, Predicta Bioactive Bulk significantly increased the surface microhardness of dentin adjacent to the restoration.
  • The authors associated this result with the combined release of fluoride, calcium, and phosphate ions.
  • The tested bioactive materials demonstrated mechanical performance comparable to the non-bioactive control, while changes in color stability and surface roughness were generally similar across the materials.
“

It is expected that the synergetic effects between different remineralizing ions released by Predicta contributed to the significant increase in dentin microhardness.

“

The bioactive restorative materials tested here exhibited mechanical performance comparable to the control material with no bioactive ingredients.

Study context

This was an in vitro chemical secondary-caries model. The findings suggest potential resistance to demineralization but do not prove prevention of secondary caries in patients.

Reference

Ibrahim, M. S., Aldhafeeri, F. R., Banaemah, A. S., Alhaider, M. S., Al-Dulaijan, Y. A., & Balhaddad, A. A. (2024). The demineralization resistance and mechanical assessments of different bioactive restorative materials for primary and permanent teeth: An in vitro study. BDJ Open, 10, Article 30.


View Published Study

Mechanical properties of modern restorative “bioactive” dental materials: An in vitro study
Radwanski et al. · 2025 · Scientific Reports

Radwanski et al. compared Predicta Bulk Bioactive, Filtek Supreme Flow, Activa Bioactive Restorative, and Beautifil Flow Plus F00 and F03.

Key findings
  • Predicta recorded the highest flexural strength at 120.40 MPa.
  • Predicta recorded the highest modulus of elasticity at 7.27 GPa.
  • Its diametral tensile strength was 47.08 MPa, comparable to Filtek Supreme Flow at 47.74 MPa.
  • Predicta and Filtek showed significantly higher flexural and diametral tensile strength than the other tested materials and significantly lower sorption in saliva and alcohol.
“

The highest median value of FS was 120.40 MPa for Predicta Bulk Bioactive.

“

Predicta Bulk Bioactive and Filtek Supreme Flow exhibited significantly lower saliva and alcohol sorption.

Study context

This was an in vitro study and does not establish long-term clinical performance.

Reference

Radwanski, M., Zmyslowska-Polakowska, E., Osica, K., Krasowski, M., Sauro, S., Hardan, L., & Lukomska-Szymanska, M. (2025). Mechanical properties of modern restorative “bioactive” dental materials: An in vitro study. Scientific Reports, 15, Article 3552.


View Published Study