C&B Metabond

499.07

SKU: S380-RD Category:

C&B Metabond R&D cement system for in vivo brain research. Bonds metals to skull/bone without glue. Developed with European neuroscientists for lab use.

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Includes, “B” Quick Base (10 ml), Catalyst (0.7 ml), Radiopaque L-Powder (5 gm), Clear L-Powder (3 gm), Adjustable Applicator Brushes, Disposable Applicator Brush Tips, Ceramic Mixing Dish with Thermometer & Mixing & Application Accessory Kit.

Description

C&B Metabond R&D

The C&B Metabond R&D a dental adhesive for rodent surgery stands as the gold standard for adhesive bonding in neuroscience and brain research. Nearly all major U.S. and international institutions—including Oxford University, the NIH, Karolinska Institutet and the Allen Institute—use and rely on this adhesive luting cement. It is engineered to bond any substrate to skull or bone, especially metals, with outstanding strength and stability.

In contrast to acrylic systems, which often require glue layers or complicated handling, C&B Metabond R&D offers a cleaner, stronger, and more direct bond—without the need for additional adhesives. The R&D kit was developed in collaboration with European neuroscientists to meet the specific needs of in vivo research. As a result, this version includes only the components necessary for experimentation, avoiding all unnecessary materials and eliminating clinical waste.

 For European Researchers Only

Please note: C&B Metabond Mouse Surgery Adhesive is not CE-marked and is not approved for dental use in Europe. It is intended exclusively for non-human research applications.

What’s Included in the C&B Metabond R&D a dental adhesive for rodent surgery (Item # S380-RD):

  • (1) “B” Quick Base (10 ml)

  • (1) Catalyst (0.7 ml)

  • (1) Radiopaque L-Powder (5 gm)

  • (1) Clear L-Powder (3 gm)

  • (50) Adjustable Applicator Brushes

  • (100) Disposable Applicator Brush Tips

  • (1) Ceramic Mixing Dish with Thermometer

  • (1) Mixing & Application Accessory Kit

Refills & Accessories (available separately)

You can reorder all components individually, including brush tips, powders, dentin activator, and mixing kits. Parkell Europe ships these articles worldwide, orders typically deliver in approximately one to two weeks. [Click here to purchase refills & accessories separately.]

Referenced in Leading Scientific Protocols

C&B Metabond has appeared in dozens of published neuroscience studies, including research conducted by the Allen Institute, International Brain Laboratory, and Oxford University. Scientists cite it consistently for its stability, reliability, and clean handling during cranial implant surgeries and long-term recordings.

Order C&B Metabond® R&D for high-performance adhesive stability in non-dental, research-based neurobiology applications worldwide.

A selection of article links related to the use of C&B Metabond R&D as a dental adhesive for rodent surgery can be found below:

Allen Institute for the Brain : A Standardized Head-Fixation System for Performing Large-Scale, In Vivo Physiological Recordings in Mice.

International Brain Laboratory Protocol: 2020: Appendix 1: IBL protocol for headbar implant surgery in mice, v4.

Barkus et al. (2022): Refinements to rodent head fixation and fluid/food control for neuroscience.

Coelho-Santos et al. (2022): Reinforced thinned-skull window for repeated imaging of the neonatal mouse brain.

Silasi et al. (2016): Intact skull chronic windows for mesoscopic wide-field imaging in awake mice.

Goldey et al. (2014): Long-term imaging in awake mice using removable cranial windows.

Wang et al (2022): Protocol for recording epileptiform discharges of EEG and behavioral seizures in freely moving mice. STAR Protocol.

Order C&B Metabond® R&D for high-performance adhesive stability in non-dental, research-based neurobiology applications across Europe.

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FAQ

C&B-Metabond® is a dental adhesive cement system developed by Parkell, Inc. It's renowned for its strong and durable bond between metals and bone, making it ideal for various neuroscience applications, including head fixation in rodent models.

Researchers apply C&B-Metabond® to securely attach headbars or other fixation devices to the skulls of mice. This ensures stable head fixation during in vivo physiological recordings and behavioral experiments.

Unlike acrylics, which require intermediate layers and can be messy, C&B-Metabond® creates a strong, durable bond without extra steps. Its biocompatibility and high bond strength make it a trusted choice for researchers worldwide.

Yes, several protocols detail its use. For example, the International Brain Laboratory provides a protocol for headbar implant surgery in mice, highlighting the effectiveness of C&B-Metabond® in their procedures.

For detailed information, including product specifications and purchasing options, visit here.

C&B-Metabond® is known for its exceptional bond strength and biocompatibility, making it ideal for sensitive research applications. It forms a stable hybrid layer that ensures reliable adhesion, which is crucial for procedures like head fixation in rodent models.

Unlike dental acrylics, which can be messy and require intermediate layers, C&B-Metabond® offers a streamlined application process. It eliminates the need for multiple steps, providing a cleaner and more efficient bonding experience.

C&B-Metabond® comes with a range of accessories, including adjustable applicator brushes, a ceramic mixing dish with a built-in thermometer, and different powder formulations. These accessories ensure precision and ease of use in the lab.

Yes, several published protocols, such as those from the International Brain Laboratory, outline the use of C&B-Metabond® for head fixation in rodents, making it a trusted choice in the research community.

C&B Metabond's consistent performance and strong adhesion help minimize variability, ensuring that researchers can achieve reproducible results across different experiments